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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 858515Generated: October 27, 2026

1-methyl-1H-imidazole-4-sulfonamide → 2-{4-[6-Chloro-2-ethyl-5-(trifluoromethyl)-1H-benzimidazol-1-YL]phenyl}ethyl-(1-methyl-1H-imidazol-4-YL)sulfonylcarbamate

https://huagongshe.com/reaction/858515

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-methyl-1H-imidazole-4-sulfonamideHCID 2736885—
Reactant2-{4-[6-chloro-2-ethyl-5-(trifluoromethyl)-1H-benzimidazol-1-yl]phenyl}ethyl phenyl carbonateHCID 21876409—
Product2-{4-[6-Chloro-2-ethyl-5-(trifluoromethyl)-1H-benzimidazol-1-YL]phenyl}ethyl-(1-methyl-1H-imidazol-4-YL)sulfonylcarbamateHCID 21875691—

Reaction Steps

The title compound was prepared according to the procedure described in step 2 of Example 243 from 2-{4-[6-chloro-2-ethyl-5-(trifluoromethyl)-1H-benzimidazol-1-yl]phenyl}ethyl phenyl carbonate and 1-methyl-1H-imidazol-4-ylsulfonamide.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07148234B2
Source datasetuspto-grants-2006_12
ORD IDord-dab71bc3889c44d1874d23ad8e188967
Source noteuspto-grants-2006_12