4-Aminophenethyl alcohol → 2-[4-(3-Cyano-2-nitroanilino)phenyl]ethanol

HRID 858524Notes

Reaction equation

HRID 858524 reaction equation
Cl[C:2]1[C:3]([N+:10]([O-:12])=[O:11])=[C:4]([CH:7]=[CH:8][CH:9]=1)[C:5]#[N:6].[NH2:13][C:14]1[CH:19]=[CH:18][C:17]([CH2:20][CH2:21][OH:22])=[CH:16][CH:15]=1>>[C:5]([C:4]1[C:3]([N+:10]([O-:12])=[O:11])=[C:2]([CH:9]=[CH:8][CH:7]=1)[NH:13][C:14]1[CH:19]=[CH:18][C:17]([CH2:20][CH2:21][OH:22])=[CH:16][CH:15]=1)#[N:6]

Participants

3

Reactant 2

HCID 669044-Aminophenethyl alcoholHCID 218758793-Chloro-2-nitrobenzonitrile

Product 1

HCID 218765262-[4-(3-Cyano-2-nitroanilino)phenyl]ethanol

Procedure

The title compound was prepared according to the procedure described in step 3 of Example 1 from 3-chloro-2-nitrobenzonitrile (step 2) and 4-aminophenylethyl alcohol.

Sources & evidence

ORD record
ord-42c43b0eb2be4d078d4dae8761a32016
Source dataset
uspto-grants-2006_12
Patent number
US07148234B2

Reaction notes

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