HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Bromobutyrate → [2-Chloro-4-(3-cyclopentyl-3-oxo-propyl)-phenoxy]-acetic acid methyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Bromobutyrate | HCID 152317 | — |
| Reactant | 4-Bromo-2-fluorophenol | HCID 2724981 | — |
| Reactant | 3-(3-Chloro-4-hydroxyphenyl)-1-cyclopentylpropan-1-one | HCID 58762696 | — |
| Product | [2-Chloro-4-(3-cyclopentyl-3-oxo-propyl)-phenoxy]-acetic acid methyl ester | HCID 58762565 | 78% |
Reaction Steps
The title compound was prepared analogously to Step 1 from Example A(52), where 3-(3-Chloro-4-hydroxy-phenyl)-1-cyclopentyl-propan-1-one was substituted for 4-Bromo-2-fluorophenol and methyl bromo acetate was substituted for methyl □-bromobutyrate in Step 1 of that example. Yield 78%.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07148226B2 |
| Source dataset | uspto-grants-2006_12 |
| ORD ID | ord-b17eb2160b4a4e7a886e03c8929ee153 |
| Source note | uspto-grants-2006_12 |