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HRID858695

反应详情

EQUATION

反应方程式

HRID 858695 的结构方程式

REACTANTS

反应物

3
结构：CC1(C)OC(=O)C=C(CC(O)(C#Cc2ccc(C3(C#N)CCC3)c(F)c2)C2CCCC2)O1
HCID58762299

未命名化合物

结构：CC(C#N)c1ccc(Br)cc1F
HCID58762345

4-Bromo-2-fluoro-α-methylbenzeneacetonitrile

C9H7BrFN

结构：N#CC1(c2ccc(Br)cc2F)CCC1
HCID58762653

未命名化合物

PRODUCTS

生成物

1
结构：CC(C#N)c1ccc(C#CC(O)(CC2=CC(=O)OC(C)(C)O2)C2CCCC2)cc1F
HCID58762558

未命名化合物

PROCEDURE

实验过程

The title compound was prepared analogously to 1-{4-[3-Cyclopentyl-4-(2,2-dimethyl-6-oxo-6H-[1,3]dioxin-4-yl)-3-hydroxy-but-1-ynyl]-2-fluoro-phenyl}-cyclobutanecarbonitrile in step 3 of example A(236) substituting 2-(4-bromo-2-fluoro-phenyl)-propionitrile from step 1 below in place of 1-(4-bromo-2-fluoro-phenyl)-cyclobutanecarbonitrile. MS (ESI): 437.0 (M+H+).