HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl iodide → 2-(4-Bromo-2-fluorophenyl)propanenitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl iodide | HCID 6328 | — |
| Reactant | 1-(4-Bromo-2-fluorophenyl)cyclobutanecarbonitrile | HCID 58762653 | — |
| Product | 2-(4-Bromo-2-fluorophenyl)propanenitrile | HCID 58762345 | — |
Reaction Steps
The title compound was prepared analogously to 1-(4-Bromo-2-fluoro-phenyl)-cyclobutanecarbonitrile in step 2 of example A(236) substituting iodomethane in place of 1,3-dibromopropane. MS (APCI): 253 (M+H+), 255 (M+2+H+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07148226B2 |
| Source dataset | uspto-grants-2006_12 |
| ORD ID | ord-52dae8af7d194e8db6ad2be4dded92e6 |
| Source note | uspto-grants-2006_12 |