Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
4-(1H-1,2,4-triazol-1-yl)benzaldehyde → 6-[2-(3-Chloro-4-methoxy-phenyl)-ethyl]-6-cyclopentyl-4-hydroxy-3-(4-[1,2,4]triazol-1-yl-benzyl)-5,6-dihydro-pyran-2-one
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 4-(1H-1,2,4-triazol-1-yl)benzaldehyde | HCID 2776488 | — |
| 반응물 | 6-(3-chloro-4-methoxyphenethyl)-6-cyclopentyl-dihydro-3H-pyran-2,4-dione | HCID 16076109 | — |
| 생성물 | 6-[2-(3-Chloro-4-methoxy-phenyl)-ethyl]-6-cyclopentyl-4-hydroxy-3-(4-[1,2,4]triazol-1-yl-benzyl)-5,6-dihydro-pyran-2-one | HCID 58762271 | — |
반응 단계
The title compound was prepared by coupling 6-[2-(3-Chloro-4-methoxy-phenyl)-ethyl]-6-cyclopentyl-dihydro-pyran-2,4-dione from Step 1 of Example B(13), to 4-[1,2,4]Triazol-1-yl -benzaldehyde using the Me2NHBH3 method described in the synthesis of Example B(31).ESIMS (MH+): 509.1.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07148226B2 |
| 출처 데이터셋 | uspto-grants-2006_12 |
| ORD ID | ord-57b549b14af14fa8bca9b48a1eafbd94 |
| 출처 메모 | uspto-grants-2006_12 |