S-2-Pyridinyl 4-bromo-2-chlorobenzenecarbothioate → 1-(4-Bromo-2-chlorophenyl)ethan-1-one

Participants

Reaction Steps

The title compound was prepared analogously to Step 2 from Example X(X): 6-Cyclopentyl-3-(5,7-dimethyl-[1,2,4]triazolo[1,5-a]pyrimidin-2-ylmethyl)-6-{2-[3-fluoro-4-(1-hydroxy-ethyl)-phenyl]-ethyl}-4-hydroxy-5,6-dihydro-pyran-2-one where 4-Bromo-2-chloro-thiobenzoic acid S-pyridin-2-yl ester (described in step 1 below) was substituted in place of 4-Bromo-2-fluoro-thiobenzoic acid S-pyridin-2-yl ester. 1H NMR (CDCl3) δ 2.64 (s, 3H), 7.46–7.48 (m,2H), 7.61 (s, 1H). ESIMS (MH+): 234.1.

Provenance & Evidence