3-Chloro-6-ethyl-4-hydroxy-6-methyl-5,6-dihydro-pyran-2-one → 3-(5-Chloro-1-isopropyl-1H-benzoimidazol-2-ylsulfanyl)-6-ethyl-4-hydroxy-6-methyl-5,6-dihydro-pyran-2-one

HRID 858803Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 858803
Cl[C:2]1[C:3](=[O:12])[O:4][C:5]([CH2:10][CH3:11])([CH3:9])[CH2:6][C:7]=1[OH:8].[Cl:13][C:14]1[CH:26]=[CH:25][C:17]2[N:18]([CH:22]([CH3:24])[CH3:23])[C:19]([SH:21])=[N:20][C:16]=2[CH:15]=1>>[Cl:13][C:14]1[CH:26]=[CH:25][C:17]2[N:18]([CH:22]([CH3:24])[CH3:23])[C:19]([S:21][C:2]3[C:3](=[O:12])[O:4][C:5]([CH2:10][CH3:11])([CH3:9])[CH2:6][C:7]=3[OH:8])=[N:20][C:16]=2[CH:15]=1

Komponenten

3

Edukt 2

HCID 587624553-Chloro-6-ethyl-4-hydroxy-6-methyl-5,6-dihydro-pyran-2-oneHCID 178456613HCID 178456613, Verbindung

Produkt 1

HCID 587622953-(5-Chloro-1-isopropyl-1H-benzoimidazol-2-ylsulfanyl)-6-ethyl-4-hydroxy-6-methyl-5,6-dihydro-pyran-2-one

Versuchsvorschrift

The title compound was prepared from 3-Chloro-6-ethyl-4-hydroxy-6-methyl-5,6-dihydro-pyran-2-one (from Step 1) and 5-Chloro-1-isopropyl-1H-benzoimidazole-2-thiol using the coupling method described in Example C(4).

Quellen und Nachweise

ORD-Eintrag
ord-ea391a4d49a7411da5ac220a0ffce214
Quelldatensatz
uspto-grants-2006_12
Patentnummer
US07148226B2

Notizen zur Reaktion

Wird geladen…