[2-(2-Cyclopentyl-4,6-dioxo-tetrahydro-pyran-2-yl)-ethyl]-carbamic Acid Tert-Butyl Ester → HCID 68867536, compound

HRID 858877Notes

Reaction equation

HRID 858877 reaction equation
C(OC(=O)[NH:7][CH2:8][CH2:9][C:10]1([CH:18]2[CH2:22][CH2:21][CH2:20][CH2:19]2)[CH2:15][C:14](=[O:16])[CH2:13][C:12](=[O:17])[O:11]1)(C)(C)C>C(O)(C(F)(F)F)=O.C(Cl)Cl>[NH2:7][CH2:8][CH2:9][C:10]1([CH:18]2[CH2:22][CH2:21][CH2:20][CH2:19]2)[O:11][C:12](=[O:17])[CH2:13][C:14](=[O:16])[CH2:15]1

Participants

3

Reactant 1

HCID 58762283[2-(2-Cyclopentyl-4,6-dioxo-tetrahydro-pyran-2-yl)-ethyl]-carbamic Acid Tert-Butyl Ester

Product 1

HCID 68867536HCID 68867536, compound

Reagents, catalysts & solvents 1

HCID 21863450Trifluoroacetic acid methylene chlorideSolvent

Procedure

A solution of [2-(2-cyclopentyl-4,6-dioxo-tetrahydro-pyran-2-yl)-ethyl]-carbamic acid tert-butyl ester (1.0 g, 2.8 mmol) from Step 4 above in 10% TFA/CH2Cl2 was stirred at room temperature for 20 minutes. The reaction was concentrated by rotary evaporation and used as is without further purification.

Workup

  1. concentrationThe reaction was concentrated by rotary evaporation
  2. customas is without further purification

Sources & evidence

ORD record
ord-78d49e4acb064cb9a140c4b36d9023aa
Source dataset
uspto-grants-2006_12
Patent number
US07148226B2

Reaction notes

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