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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 858922Generated: October 25, 2026

(RS)-1-(4-hydroxyphenyl)-5-oxo-pyrrolidine-3-carboxylic acid ethyl ester → Methyl 1-(4-hydroxyphenyl)-5-oxopyrrolidine-3-carboxylate

https://huagongshe.com/reaction/858922

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(RS)-1-(4-hydroxyphenyl)-5-oxo-pyrrolidine-3-carboxylic acid ethyl esterHCID 69491868—
SolventEthanolHCID 702—
ProductMethyl 1-(4-hydroxyphenyl)-5-oxopyrrolidine-3-carboxylateHCID 2883518—

Reaction Steps

In an analogous manner to that described in Example 1 b), the (RS)-1-(4-hydroxyphenyl)-5-oxo-pyrrolidine-3-carboxylic acid ethyl ester was obtained by reaction of the crude (RS)-1-(4-hydroxyphenyl)-5-oxo-pyrrolidine-3-carboxylic acid with ethanol as a white solid; MS: m/e=248 (M−H)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07148362B2
Source datasetuspto-grants-2006_12
ORD IDord-b3466723e32c496baaea73451607b328
Source noteuspto-grants-2006_12