HCID 23233793, compound → HCID 13135817, compound

HRID 859225Notes

Reaction equation

HRID 859225 reaction equation
[F:1][C:2]1[CH:7]=[CH:6][CH:5]=[C:4](/[CH:8]=[CH:9]/[C:10]2[CH:15]=[CH:14][C:13]([N+:16]([O-])=O)=[CH:12][CH:11]=2)[CH:3]=1>[Pd]>[F:1][C:2]1[CH:3]=[C:4]([CH2:8][CH2:9][C:10]2[CH:11]=[CH:12][C:13]([NH2:16])=[CH:14][CH:15]=2)[CH:5]=[CH:6][CH:7]=1

Participants

3

Reactant 1

HCID 23233793HCID 23233793, compound

Product 1

HCID 13135817HCID 13135817, compound

Reagents, catalysts & solvents 1

HCID 23938PalladiumCatalyst

Procedure

In an analogous manner to that described in Example 18b), the hydrogenation of (E)-1-fluoro-3-[2-(4-nitrophenyl)ethenyl]-benzene [Example 18a)] using palladium on carbon (10%) during 5 hours and simultaneous reduction of the double bond yields quantitatively 4-[2-(3-fluoro-phenyl)-ethyl]-phenylamine as a yellow solid. MS: m/e=215 (M)+.

Workup

  1. customduring 5 hours

Sources & evidence

ORD record
ord-ae21671af0d1437ca4e36b12813dae64
Source dataset
uspto-grants-2006_12
Patent number
US07151111B2

Reaction notes

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