Furan-2-boronic acid → (4-Furan-2-yl-2-nitro-phenyl)-carbamic acid tert.-butyl ester

HRID 859253Notes

Reaction equation

HRID 859253 reaction equation
[C:1]([O:5][C:6](=[O:18])[NH:7][C:8]1[CH:13]=[CH:12][C:11](I)=[CH:10][C:9]=1[N+:15]([O-:17])=[O:16])([CH3:4])([CH3:3])[CH3:2].[O:19]1[CH:23]=[CH:22][CH:21]=[C:20]1B(O)O>>[C:1]([O:5][C:6](=[O:18])[NH:7][C:8]1[CH:13]=[CH:12][C:11]([C:20]2[O:19][CH:23]=[CH:22][CH:21]=2)=[CH:10][C:9]=1[N+:15]([O-:17])=[O:16])([CH3:4])([CH3:3])[CH3:2]

Participants

3

Reactant 2

HCID 2734357Furan-2-boronic acidHCID 23554339Tert-butyl (4-iodo-2-nitrophenyl)carbamate

Product 1

HCID 69592762(4-Furan-2-yl-2-nitro-phenyl)-carbamic acid tert.-butyl ester

Procedure

Prepared from (4-iodo-2-nitro-phenyl)-carbamic acid tert.-butyl ester (Example A1) and furan-2-boronic acid according to the general procedure B. Obtained as an orange solid (282 mg).

Sources & evidence

ORD record
ord-154013d8ac2b4fadb5340cb9580da94d
Source dataset
uspto-grants-2006_12
Patent number
US07151098B2

Reaction notes

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