Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 859259Generated: October 30, 2026

4-(Trifluoromethoxy)phenylboronic acid → (3-Nitro-4'-trifluoromethoxy-biphenyl-4-yl)-carbamic acid tert.-butyl ester

https://huagongshe.com/reaction/859259

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(Trifluoromethoxy)phenylboronic acidHCID 2734386—
ReactantTert-butyl (4-iodo-2-nitrophenyl)carbamateHCID 23554339—
Product(3-Nitro-4'-trifluoromethoxy-biphenyl-4-yl)-carbamic acid tert.-butyl esterHCID 69592811—

Reaction Steps

Prepared from (4-iodo-2-nitro-phenyl)-carbamic acid tert.-butyl ester (Example A1) and 4-(trifluoromethoxy)benzene boronic acid according to the general procedure B. Obtained as an orange solid (569 mg).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07151098B2
Source datasetuspto-grants-2006_12
ORD IDord-592a4d655b1c4f80b7215bf986bcfab7
Source noteuspto-grants-2006_12