HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Bromopyridine → (2-Nitro-4-pyridin-2-ylethynyl-phenyl)-carbamic acid tert.-butyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Bromopyridine | HCID 7973 | — |
| Reactant | tert-Butyl (4-ethynyl-2-nitrophenyl)carbamate | HCID 23554338 | — |
| Product | (2-Nitro-4-pyridin-2-ylethynyl-phenyl)-carbamic acid tert.-butyl ester | HCID 69592858 | 86.3% |
Reaction Steps
Prepared from (4-ethynyl-2-nitro-phenyl)-carbamic acid tert.-butyl ester (Example F2) (262 mg, 1.0 mmol) and 2-bromopyridine (0.15 mL, 1.6 mmol) according to the general procedure F. Obtained as a yellow solid (293 mg).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07151098B2 |
| Source dataset | uspto-grants-2006_12 |
| ORD ID | ord-dc0bc078b7fb4ef4af8928a193087666 |
| Source note | uspto-grants-2006_12 |