HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Iodo-4-(trifluoromethoxy)benzene → [2-Nitro-4-(4-trifluoromethoxy-phenylethynyl)-phenyl]-carbamic acid tert.-butyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Iodo-4-(trifluoromethoxy)benzene | HCID 2777294 | — |
| Reactant | tert-Butyl (4-ethynyl-2-nitrophenyl)carbamate | HCID 23554338 | — |
| Product | [2-Nitro-4-(4-trifluoromethoxy-phenylethynyl)-phenyl]-carbamic acid tert.-butyl ester | HCID 69592769 | 97.5% |
Reaction Steps
Prepared from (4-ethynyl-2-nitro-phenyl)-carbamic acid tert.-butyl ester (Example F2) (701 mg, 2.67 mmol) and 1-iodo-4-(trifluoromethoxy)benzene (1.0 g, 3.47 mmol) according to the general procedure F. Obtained as a yellow solid (1.10 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07151098B2 |
| Source dataset | uspto-grants-2006_12 |
| ORD ID | ord-12f3d6c90bc146a6bc65a45a6739627f |
| Source note | uspto-grants-2006_12 |