(4-Furan-2-yl-2-nitro-phenyl)-carbamic acid tert.-butyl ester → (2-Amino-4-furan-2-yl-phenyl)-carbamic acid tert.-butyl ester

HRID 859304Notes

Reaction equation

HRID 859304 reaction equation
[C:1]([O:5][C:6](=[O:22])[NH:7][C:8]1[CH:13]=[CH:12][C:11]([C:14]2[O:15][CH:16]=[CH:17][CH:18]=2)=[CH:10][C:9]=1[N+:19]([O-])=O)([CH3:4])([CH3:3])[CH3:2]>[Ni]>[C:1]([O:5][C:6](=[O:22])[NH:7][C:8]1[CH:13]=[CH:12][C:11]([C:14]2[O:15][CH:16]=[CH:17][CH:18]=2)=[CH:10][C:9]=1[NH2:19])([CH3:4])([CH3:2])[CH3:3]

Participants

3

Reactant 1

HCID 69592762(4-Furan-2-yl-2-nitro-phenyl)-carbamic acid tert.-butyl ester

Product 1

HCID 69592822(2-Amino-4-furan-2-yl-phenyl)-carbamic acid tert.-butyl ester

Reagents, catalysts & solvents 1

HCID 935NickelCatalyst

Procedure

Prepared from (4-furan-2-yl-2-nitrophenyl)-carbamic acid tert.-butyl ester (Example B3) by catalytic hydrogenation with Raney-Ni according to the general procedure G (method a). Obtained as a grey powder (212 mg).

Sources & evidence

ORD record
ord-effef10f896a46cea6b8864a13adcaf0
Source dataset
uspto-grants-2006_12
Patent number
US07151098B2

Reaction notes

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