HuagongsheHuagongshe Chemistry Print Report · For research reference only
(2'-Chloro-3-nitro-biphenyl-4-yl)-carbamic acid tert.-butyl ester → Carbamic acid,(3-amino-2'-chloro[1,1'-biphenyl]-4-yl)-,1,1-dimethylethyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (2'-Chloro-3-nitro-biphenyl-4-yl)-carbamic acid tert.-butyl ester | HCID 69592813 | — |
| Catalyst | Nickel | HCID 935 | — |
| Product | Carbamic acid,(3-amino-2'-chloro[1,1'-biphenyl]-4-yl)-,1,1-dimethylethyl ester | HCID 69592803 | — |
Reaction Steps
Prepared from (2′-chloro-3-nitro-biphenyl-4-yl)-carbamic acid tert.-butyl ester (Example C8) by catalytic hydrogenation with Raney-Ni according to the general procedure G (method a). Obtained as a white solid (180 mg).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07151098B2 |
| Source dataset | uspto-grants-2006_12 |
| ORD ID | ord-cfec54c10c6b4d5b969abe2a0e5db1aa |
| Source note | uspto-grants-2006_12 |