HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
Stannous chloride dihydrate → [2-Amino-4-(4-fluoro-phenylethynyl)-phenyl]-carbamic acid tert-butyl ester
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | Stannous chloride dihydrate | HCID 61436 | — |
| Edukt | [4-(4-Fluoro-phenylethynyl)-2-nitro-phenyl]-carbamic acid tert.-butyl ester | HCID 69592817 | — |
| Produkt | [2-Amino-4-(4-fluoro-phenylethynyl)-phenyl]-carbamic acid tert-butyl ester | HCID 69486641 | 77,2% |
Reaktionsschritte
Prepared from [4-(4-fluoro-phenylethynyl)-2-nitro-phenyl]-carbamic acid tert.-butyl ester (Example F9) (10.0 g, 28.1 mmol) by reduction with SnCl2.2H2O (31.7 g, 140.5 mmol) according to the general procedure G (method b). Obtained as a yellow solid (7.08 g).
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US07151098B2 |
| Quelldatensatz | uspto-grants-2006_12 |
| ORD ID | ord-5601d72cf78d4259a466c81ba76d5a79 |
| Quellennotiz | uspto-grants-2006_12 |