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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 859390Generated: October 25, 2026

Ethyl 3-(3-cyanophenyl)-3-oxopropanoate → {2-[3-(3-Cyano-phenyl)-3-oxo-propionylamino]-4-furan-3-yl-phenyl}-carbamic acid tert.-butyl ester

https://huagongshe.com/reaction/859390

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthyl 3-(3-cyanophenyl)-3-oxopropanoateHCID 11622629—
Reactant(2-Amino-4-furan-3-yl-phenyl)-carbamic acid tert.-butyl esterHCID 69592861—
Product{2-[3-(3-Cyano-phenyl)-3-oxo-propionylamino]-4-furan-3-yl-phenyl}-carbamic acid tert.-butyl esterHCID 86587998—

Reaction Steps

Prepared from (2-amino-4-furan-3-yl-phenyl)-carbamic acid tert.-butyl ester (Example G11) and 3-(3-cyano-phenyl)-3-oxo-propionic acid ethyl ester (Pol. J. Chem. 1978, 25) according to the general procedure K. Obtained as an orange solid (460 mg).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07151098B2
Source datasetuspto-grants-2006_12
ORD IDord-3823be15b6924b5d88a48a61776281fd
Source noteuspto-grants-2006_12