HuagongsheHuagongshe Chemistry Print Report · For research reference only
(2-Amino-4-phenylethynyl-phenyl)-carbamic acid tert-butyl ester → {2-[3-(3-Nitro-phenyl)-3-oxo-propionylamino]-4-phenylethynyl-phenyl}-carbamic acid tert.-butyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (2-Amino-4-phenylethynyl-phenyl)-carbamic acid tert-butyl ester | HCID 11404065 | — |
| Reactant | HCID 22224811 | HCID 22224811 | — |
| Product | {2-[3-(3-Nitro-phenyl)-3-oxo-propionylamino]-4-phenylethynyl-phenyl}-carbamic acid tert.-butyl ester | HCID 86588018 | 49.5% |
Reaction Steps
Prepared from (2-amino-4-phenylethynyl-phenyl)-carbamic acid tert.-butyl ester (Example G2) (1.1 g, 4.0 mmol) and 2,2-dimethyl-6-(3-nitro-phenyl)-[1,3]dioxin-4-one (Example J12) (1.23 g, 4.4 mmol) according to the general procedure K. Obtained as a light yellow solid (989 mg).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07151098B2 |
| Source dataset | uspto-grants-2006_12 |
| ORD ID | ord-0612bece5d9548a5b3d1c983c5f073a5 |
| Source note | uspto-grants-2006_12 |