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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 859554Generated: October 29, 2026

Trifluoroacetic acid → HCID 22224788, compound

https://huagongshe.com/reaction/859554

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTrifluoroacetic acidHCID 6422—
ReactantHCID 86588048HCID 86588048—
SolventDichloromethaneHCID 6344—
ProductHCID 22224788HCID 22224788—

Reaction Steps

Prepared from {3-[3-(2-cyano-pyridin-4-yl)-3-oxo-propionylamino]-4′-fluoro-biphenyl-4-yl}-carbamic acid tert.-butyl ester (Example K63) by treatment with TFA in CH2Cl2 according to the general procedure M. Obtained as an orange solid (23 mg).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07151098B2
Source datasetuspto-grants-2006_12
ORD IDord-7134121ece3448a69818fc5dfa7dc43a
Source noteuspto-grants-2006_12