反应详情

To a slurry of (5-amino-1H-[1,2,4]triazol-3-yl)-methanol (9.5 g, 50 mmol) from step 6 above in acetic acid (200 mL) was added 2,4-pentanedione (5.13 mL, 50 mmol). The mixture was heated to reflux for 4 hours, and then cooled to room temperature. The product was isolated by removing the solvent by rotary evaporation (8.5 g, 95% yield). MS (ESI): 179 (M+H).

1. temperatureThe mixture was heated
2. temperatureto reflux for 4 hours
3. customThe product was isolated
4. customby removing the solvent
5. customby rotary evaporation (8.5 g, 95% yield)