HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → 3,4-Dihydro-2H-pyrido[3,2-b]-1,4-oxazine-6-pentanoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | HCID 20622482 | HCID 20622482 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | 3,4-Dihydro-2H-pyrido[3,2-b]-1,4-oxazine-6-pentanoic acid | HCID 23435508 | — |
Reaction Steps
A solution of 4-6 (0.223 mmol) and 1.0 N NaOH solution (0.268 mL, 0.268 mmol) in MeOH (1.5 mL) was stirred overnight. The reaction was neutralized by adding 1.0 N HCl solution (0.268 mL, 0.268 mmol) then concentrated and used in Step G without further purification.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07153862B2 |
| Source dataset | uspto-grants-2006_12 |
| ORD ID | ord-4f9b3f5d4ae64e5ebf7c69d6b71ab343 |
| Source note | uspto-grants-2006_12 |