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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 860112Generated: October 25, 2026

Benzaldehyde → HCID 178418850, compound

https://huagongshe.com/reaction/860112

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzaldehydeHCID 240—
ReactantAcetyl chlorideHCID 6367—
Reactant2-AminopyrimidineHCID 7978—
ReactantCyclohexyl isocyanideHCID 79129—
SolventPerchloric AcidHCID 24247—
ProductHCID 178418850HCID 178418850—

Reaction Steps

Example 6 was carried out in accordance with the general directions for synthesis in process step a) from 1.0 ml (0.1 mmol) 2-amino-pyrimidine (0.1 M, DCM), 0.575 ml (0.115 mmol) cyclohexylisonitrile solution (0.2 M, DCM), 0.500 ml (0.15 mmol) benzaldehyde solution (0.3 M, DCM) and 10 μl perchloric acid (w=20%) and in process step c) and d) by reacting the resultant reaction product with 0.4 mmol acetylchloride.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07153873B2
Source datasetuspto-grants-2006_12
ORD IDord-5a3f58d8d6c543708c83bb8200d6c370
Source noteuspto-grants-2006_12