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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 860116Generated: October 27, 2026

Benzaldehyde → HCID 178418783, compound

https://huagongshe.com/reaction/860116

Reaction equation

Participants

RoleNameHCIDCharge
ReactantBenzaldehydeHCID 240—
Reactant2-AminopyridineHCID 10439—
ReactantTert-Butyl isocyanideHCID 23577—
ReactantCyclohexanecarbonyl chlorideHCID 75938—
SolventPerchloric AcidHCID 24247—
ProductHCID 178418783HCID 178418783—

Reaction Steps

Example 10 was carried out in accordance with the general directions for synthesis in process step a) from 1.0 ml (0.1 mmol) 2-amino-pyridine (0.1 M, DCM), 0.575 ml (0.115 mmol) tert.-butylisonitrile solution (0.2 M, DCM), 0.500 ml (0.15 mmol) benzaldehyde solution (0.3 M, DCM) and 10 μl perchloric acid (w=20%) and in process steps b) to d) by reacting the resultant reaction product with 0.4 mmol cyclohexylcarboxylic acid chloride.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07153873B2
Source datasetuspto-grants-2006_12
ORD IDord-1a8eb10098814a43a5edacbc0c14f9af
Source noteuspto-grants-2006_12