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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 860130Generated: October 27, 2026

Acetaldehyde → HCID 178419014, compound

https://huagongshe.com/reaction/860130

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAcetaldehydeHCID 177—
ReactantAcetyl chlorideHCID 6367—
Reactant2-AminopyrimidineHCID 7978—
ReactantCyclohexyl isocyanideHCID 79129—
SolventPerchloric AcidHCID 24247—
ProductHCID 178419014HCID 178419014—

Reaction Steps

Example 24 was carried out in accordance with the general directions for synthesis in process step a) from 1.0 ml (0.1 mmol) 2-amino-pyrimidine (0.1 M, DCM), 0.575 ml (0.115 mmol) cyclohexylisonitrile solution (0.2 M, DCM), 0.500 ml (0.15 mmol) acetaldehyde solution (0.3 M, DCM) and 10 μl perchloric acid (w=20%) and in process step c) and d) by reacting the resultant reaction product with 0.4 mmol acetylchloride.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07153873B2
Source datasetuspto-grants-2006_12
ORD IDord-c90f1e459b1c4f8c90e72b0fdb6eb42a
Source noteuspto-grants-2006_12