HuagongsheHuagongshe Chemistry Print Report · For research reference only
3,5-Dichloroaniline → N-(3,5-dichlorophenyl)alanine isobutyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3,5-Dichloroaniline | HCID 12281 | — |
| Reactant | Isobutyl pyruvate | HCID 83084 | — |
| Product | N-(3,5-dichlorophenyl)alanine isobutyl ester | HCID 54461425 | — |
Reaction Steps
Following General Procedure AA above and using 3,5-dichloroaniline (Aldrich) and iso-butyl pyruvate (prepared by following General Procedure AO above), the title compound was prepared as an oil. The reaction was monitored by tlc on silica gel (Rf=0.4 in 25% EtOAc/hexanes) and purification was by preparative plate chromatography (silica gel using 25% EtOAc/hexanes as the eluant).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07153847B2 |
| Source dataset | uspto-grants-2006_12 |
| ORD ID | ord-0c6be54c185c40c9b9b53cbf0a92453f |
| Source note | uspto-grants-2006_12 |