L-Alanine → N-(3-chlorophenylacetyl)alanine

HRID 860339Notes

Reaction equation

HRID 860339 reaction equation
[NH2:1][C@H:2]([C:4]([OH:6])=[O:5])[CH3:3].[Cl:7][C:8]1[CH:9]=[C:10]([CH2:14][C:15](O)=[O:16])[CH:11]=[CH:12][CH:13]=1>>[Cl:7][C:8]1[CH:9]=[C:10]([CH2:14][C:15]([NH:1][C@H:2]([C:4]([OH:6])=[O:5])[CH3:3])=[O:16])[CH:11]=[CH:12][CH:13]=1

Participants

3

Reactant 2

HCID 5950L-AlanineHCID 158793-Chlorophenylacetic acid

Product 1

HCID 15481783N-(3-chlorophenylacetyl)alanine

Procedure

The title compound was prepared using L-alanine (Nova Biochem) and 3-chlorophenyl acetic acid (Aldrich) by following General Procedures BF or BG, followed by hydrolysis using General Procedure BD.

Workup

  1. customfollowed by hydrolysis

Sources & evidence

ORD record
ord-9f150d7fe55d420db542bd1e489d0982
Source dataset
uspto-grants-2006_12
Patent number
US07153847B2

Reaction notes

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