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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 860376Generated: October 30, 2026

2-methylpropyl (2S)-2-aminopropanoate → N-[(3-phenyl-1,2,4thiadiazol-5yl)acetyl]alanine Iso-butyl Ester

https://huagongshe.com/reaction/860376

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-methylpropyl (2S)-2-aminopropanoateHCID 13743556—
Reactant2-(3-Phenyl-1,2,4-thiadiazol-5-yl)acetic acidHCID 22492184—
ProductN-[(3-phenyl-1,2,4thiadiazol-5yl)acetyl]alanine Iso-butyl EsterHCID 22894976—

Reaction Steps

Following General Procedure BI above, and using (3-phenyl-1,2,4-thiadiazol-5-yl)acetic acid (CAS# 90771-06-5) and alanine iso-butyl ester (prepared following General Procedure BJ above), the title compound was prepared. The reaction was monitored by tlc on silica gel and purification was by filtration as described in the general procedure.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07153847B2
Source datasetuspto-grants-2006_12
ORD IDord-55592942cb0f49b497f21e4ea476e235
Source noteuspto-grants-2006_12