4-Bromobenzoic acid → 1-[2-(-Bromo-phenyl)4-isopropyl-oxazol-5-yl]-ethanol

HRID 860594Notes

Reaction equation

HRID 860594 reaction equation
[Br:1]C1C=CC(C(O)=O)=CC=1.Br[C:12]1[CH:17]=[CH:16][C:15]([C:18]2[O:19][C:20]([CH:26]([OH:28])[CH3:27])=[C:21]([CH:23]([CH3:25])[CH3:24])[N:22]=2)=[CH:14][CH:13]=1>>[Br:1][C:16]1[CH:17]=[CH:12][CH:13]=[CH:14][C:15]=1[C:18]1[O:19][C:20]([CH:26]([OH:28])[CH3:27])=[C:21]([CH:23]([CH3:25])[CH3:24])[N:22]=1

Participants

3

Reactant 2

HCID 114644-Bromobenzoic acidHCID 587656641-[2-(4-Bromo-phenyl)-4-isopropyl-oxazol-5-yl]-ethanol

Product 1

HCID 690556981-[2-(-Bromo-phenyl)4-isopropyl-oxazol-5-yl]-ethanol

Procedure

By the sequence above as preparation 38, 4-bromo-benzoic acid is converted to 1-[2-(4-bromo-phenyl)-4-isopropyl-oxazol-5-yl]-ethanol.

Sources & evidence

ORD record
ord-0ddd4b8566aa4f0fb9b1d791e35b7f35
Source dataset
uspto-grants-2006_12
Patent number
US07153878B2

Reaction notes

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