HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 68843710, compound → HCID 57431983, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 68843710 | HCID 68843710 | — |
| Reactant | HCID 178418361 | HCID 178418361 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Methanol | HCID 887 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 57431983 | HCID 57431983 | 100% |
Reaction Steps
A mixture of 4-(2-methoxycarbonyl-vinyl)-3-methyl-benzoic acid benzyl ester (11.6 g, 37.4 mmol) and Pd/C (5%, 1.5 g) in THF (300 mL) and methanol (100 mL) is stirred under 60 psi of hydrogen overnight. Catalyst is filtered off, filtrate is concentrated giving the title compound (8.3 g, 100%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07153878B2 |
| Source dataset | uspto-grants-2006_12 |
| ORD ID | ord-a2060b4eba2c48dc95551d57a28770de |
| Source note | uspto-grants-2006_12 |