HuagongsheHuagongshe Chemistry Print Report · For research reference only
2,5-Dibromopyridine → 5-Bromo-2-(methylthio)pyridine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2,5-Dibromopyridine | HCID 69353 | — |
| Reactant | Sodium methylsulfide | HCID 86593196 | — |
| Solvent | Dimethyl Sulfoxide | HCID 679 | — |
| Solvent | Water | HCID 962 | — |
| Product | 5-Bromo-2-(methylthio)pyridine | HCID 11424251 | — |
Reaction Steps
To a solution of 3,6-dibromopyridine (1.0 eq.) in DMSO (0.3M) was added sodium methylsulfide (1.1 eq.). The mixture was stirred for 2 d at rt then poured in water. The resulting precipitate was filtered to afford the title compound as white solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07153968B2 |
| Source dataset | uspto-grants-2006_12 |
| ORD ID | ord-de10f32505254ca7b00fb2a492a2692d |
| Source note | uspto-grants-2006_12 |