HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl Acetate → HCID 69374948, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl Acetate | HCID 8857 | — |
| Reactant | Ethyl bromodifluoroacetate | HCID 69585 | — |
| Reactant | HCID 69374263 | HCID 69374263 | — |
| Solvent | Diethyl Ether | HCID 3283 | — |
| Product | HCID 69374948 | HCID 69374948 | — |
Reaction Steps
Prepared according to the procedure described in EXAMPLE 24 (Step 5) but using 6-(1-methanesulfonyl-1-methyl-ethyl)-8-{3-[5-(2-trimethylsilanyl-ethylsulfanyl)-pyridin-3-yl]-phenyl}-quinoline from EXAMPLE 24 (Step 2) and bromo-difluoro-acetic acid ethyl ester as starting materials. Flash chromatography (Hex:EtOAc; 1:4) and stirring in Hex:Et2O afforded the title compound as a white solid after filtration.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07153968B2 |
| Source dataset | uspto-grants-2006_12 |
| ORD ID | ord-1c01e71490ed42cf9adaf329a3e4ffeb |
| Source note | uspto-grants-2006_12 |