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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 861028Generated: October 30, 2026

Ethyl Acetate → ethyl (1R,2S)-2-(4-bromophenyl)cyclopropane-1-carboxylate

https://huagongshe.com/reaction/861028

Reaction equation

Participants

RoleNameHCIDCharge
ReactantEthyl AcetateHCID 8857—
ReactantZ-3-(4-Bromo-phenyl)-acrylic acid methyl esterHCID 1712253—
Productethyl (1R,2S)-2-(4-bromophenyl)cyclopropane-1-carboxylateHCID 66578128—

Reaction Steps

Prepared according to the procedure described in Example 42, Step 1, but using Z-3-(4-Bromo-phenyl)-acrylic acid methyl ester from Step 1 as starting material Flash chromatography (Hex:EtOAc 85:15) afforded the title compound as a oil.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07153968B2
Source datasetuspto-grants-2006_12
ORD IDord-957c96b542564d4485e8848da6d762e3
Source noteuspto-grants-2006_12