Pyrrolidine → HCID 57494734, compound

Participants

Reaction Steps

In a similar manner as described in Example 1 from 1-[2-(3-bromophenyl)-7-chloropyrazolo[1,5-a]pyridin-3-yl]ethanone (3.00 g, 8.6 mmol) and pyrrolidine, 1-[2-(3-bromophenyl)-7-(1-pyrrolidinyl)pyrazolo[1,5-a]pyridin-3-yl]ethanone (3.18 g, 96%) was obtained as a yellow syrup. 1H NMR (CDCl3): δ 7.78–7.74 (m, 2H), 7.56 (d, 1H), 7.50 (d, 1H), 7.38–7.28 (m, 2H), 6.14 (d, 1H), 3.72 (m, 4H), 2.12 (s, 3H), 1.98 (m, 4H); MS m/z 384 (M+1).

Provenance & Evidence