tert-Butyl 4-oxopiperidine-1-carboxylate → Tert-butyl 4-butyl-4-hydroxy-1-piperidinecarboxylate

HRID 86115Notes

Reaction equation

HRID 86115 reaction equation
[C:6](=[O:7])([O:8][C:9]([CH3:10])([CH3:11])[CH3:12])[N:13]1[CH2:14][CH2:15][C:16](=[O:19])[CH2:17][CH2:18]1.[CH2:1]([CH2:2][CH2:3][CH3:4])[Li:5]>>[CH2:1]([CH2:2][CH2:3][CH3:4])[C:16]1([OH:19])[CH2:15][CH2:14][N:13]([C:6](=[O:7])[O:8][C:9]([CH3:10])([CH3:11])[CH3:12])[CH2:18][CH2:17]1

Participants

3

Reactant 2

HCID 735900tert-Butyl 4-oxopiperidine-1-carboxylateHCID 178418339Butyllithium

Product 1

HCID 59438564Tert-butyl 4-butyl-4-hydroxy-1-piperidinecarboxylate

Sources & evidence

ORD record
ord-f77b1bf03e2a4a6c959648a205184e43
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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