Methyl iodide → HCID 19703219, compound

Participants

Reaction Steps

2 g of compound 4 are dissolved in 20 ml of dimethylformamide at 0° C. and 0.475 g of K2CO3 and 0.214 ml of ICH3 are added. After 24 hours at 5° C., 20 ml of H2O and 40 ml of CH2 Cl2 are added. The organic phase decanted is washed, dried and concentrated to dryness. The residue is recrystallized from (CH3)2CHOH to give 1.76 g of final product which melts at 186° C.

Provenance & Evidence