2,5-Dimethoxytetrahydrofuran → 6-(1-Pyrrolyl)-7-trifluoromethyl-2,3(1H,4H)-quinoxalinedione

HRID 861467Notes

Reaction equation

HRID 861467 reaction equation
[NH2:1][C:2]1[CH:3]=[C:4]2[C:9](=[CH:10][C:11]=1[C:12]([F:15])([F:14])[F:13])[NH:8][C:7](=[O:16])[C:6](=[O:17])[NH:5]2.CO[CH:20]1[CH2:24][CH2:23][CH:22](OC)O1>>[N:1]1([C:2]2[CH:3]=[C:4]3[C:9](=[CH:10][C:11]=2[C:12]([F:15])([F:14])[F:13])[NH:8][C:7](=[O:16])[C:6](=[O:17])[NH:5]3)[CH:20]=[CH:24][CH:23]=[CH:22]1

Participants

3

Reactant 2

HCID 790982,5-DimethoxytetrahydrofuranHCID 17800784HCID 17800784, compound

Product 1

HCID 220970866-(1-Pyrrolyl)-7-trifluoromethyl-2,3(1H,4H)-quinoxalinedione

Procedure

12.2mmol of 6-amino-7-trifluoromethyl-2,3(1H,4H)-quinoxalinedione were reacted with 12.2 mmol of 2,5-dimethoxytetrahydrofuran by the method of Example 5d.

Sources & evidence

ORD record
ord-d30dc6a87cf04f75b737df4162293c17
Source dataset
uspto-grants-1998_02
Patent number
US05714489

Reaction notes

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