反应详情

4.5 g (14.8 mmol) of 7-amino-1-cyclohexyl-6-nitro-2,3(1H,4H)-quinoxalinedione (product 37b) and 3.5 g (14.8 mmol) of 2-methoxycarbonyl-2,5-dimethoxytetrahydrofuran in 75 ml of acetic acid were refluxed for 2 h. The mixture was poured into ice-water, and the precipitate was filtered off with suction to yield 4.8 g (78%) of the product. Melting point 293° C. (decomposition).

1. filtrationthe precipitate was filtered off with suction