Ethyl Acetate → HCID 19704254, compound

Participants

Reaction Steps

3 g of the product of Stage 3 were dissolved at 30° C. in 60 ml of dioxane and the medium was allowed to return to ambient temperature. 1.56 g (2 equivalents) of MnO2 were added about every 30 minutes for about 2 hours, that being 10 equivalents in total. The mixture was poured into 500 ml of ethyl acetate and filtration was carried out. The filtrate was evaporated to dryness to obtain 2.7 g of a yellow solid which was chromatographed on silica with AcOEt/flugene (1-2) to obtain 2.1 g of the expected product (vivid yellow solid).

Provenance & Evidence