HuagongsheHuagongshe Chemistry Print Report · For research reference only
Iodoethane → 1-Ethoxy-3-fluorobenzene
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Iodoethane | HCID 6340 | — |
| Reactant | 3-Fluorophenol | HCID 9743 | — |
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Solvent | Acetone | HCID 180 | — |
| Product | 1-Ethoxy-3-fluorobenzene | HCID 136301 | — |
Reaction Steps
3-Fluorophenol (20.0 g, 178.4 mmol), ethyl iodide (83.5 g, 535.2 mmol) and K2CO3 (49.3 g, 356.8 mmol) in 250 ml of acetone were stirred at 50° C. overnight. The mixture was filtered and evaporated to give 1-ethoxy-3-fluorobenzene.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05714503 |
| Source dataset | uspto-grants-1998_02 |
| ORD ID | ord-285479cd4a8d4ddcacd5bbf1532b7b81 |
| Source note | uspto-grants-1998_02 |