HuagongsheHuagongshe Chemistry Print Report · For research reference only
Iodoethane → 5-Bromo-2-ethoxybenzyl alcohol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Iodoethane | HCID 6340 | — |
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 5-Bromo-2-hydroxybenzyl alcohol | HCID 75342 | — |
| Solvent | Acetone | HCID 180 | — |
| Product | 5-Bromo-2-ethoxybenzyl alcohol | HCID 24721639 | — |
Reaction Steps
5-Bromo-2-hydroxybenzylalcohol (5.0 g, 24.6 mmol), ethyl iodide (11.5 g, 73.8 mmol) and K2CO3 (3.4 g, 24.6 mmol) in 50 ml of acetone was stirred at +50° C. overnight. The mixture was filtered and evaporated. The product was purified by silica gel column chromatography (EtOAc/petroleum ether 30:100) to give 5-bromo-2-ethoxybenzyl alcohol.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05714503 |
| Source dataset | uspto-grants-1998_02 |
| ORD ID | ord-05b0af491b934a388520302aeb1a6f32 |
| Source note | uspto-grants-1998_02 |