HCID 45100640, compound → 3beta,16beta-Dimethyl-5alpha-androstan-17-one

HRID 861643Notes

Reaction equation

HRID 861643 reaction equation
[CH3:1][C@H:2]1[CH2:19][CH2:18][C@@:17]2([CH3:20])[C:4](=[CH:5][CH2:6][C@@H:7]3[C@@H:16]2[CH2:15][CH2:14][C@@:12]2([CH3:13])[C@H:8]3[CH2:9][C@@H:10]([CH3:22])[C:11]2=[O:21])[CH2:3]1.[H][H]>C(O)C.[Pd]>[CH3:1][C@H:2]1[CH2:19][CH2:18][C@@:17]2([CH3:20])[C@@H:4]([CH2:5][CH2:6][C@@H:7]3[C@@H:16]2[CH2:15][CH2:14][C@@:12]2([CH3:13])[C@H:8]3[CH2:9][C@H:10]([CH3:22])[C:11]2=[O:21])[CH2:3]1

Participants

5

Reactant 2

HCID 45100640HCID 45100640, compoundHCID 178418361HCID 178418361, compound

Product 1

HCID 676477863beta,16beta-Dimethyl-5alpha-androstan-17-one

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 702EthanolSolvent

Procedure

To a solution of 3β,16β-dimethylandrost-5-en-17-one prepared in Example I in 500 ml of ethanol is added 5% Pd on C and the mixture is exposed to a hydrogen atmosphere while stirring. The catalyst is filtered off and the above-identified product is isolated.

Workup

  1. filtrationThe catalyst is filtered off
  2. customthe above-identified product is isolated

Sources & evidence

ORD record
ord-ded78350cf864819bf2f0ca5624d8cb9
Source dataset
uspto-grants-1998_02
Patent number
US05714481

Reaction notes

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