HCID 4418042, compound → N2,N2-Diethylpyridine-2,5-diamine

HRID 861657Notes

Reaction equation

HRID 861657 reaction equation
[CH2:1]([N:3]([CH2:13][CH3:14])[C:4]1[CH:9]=[CH:8][C:7]([N+:10]([O-])=O)=[CH:6][N:5]=1)[CH3:2]>CO.[Pd]>[NH2:10][C:7]1[CH:8]=[CH:9][C:4]([N:3]([CH2:13][CH3:14])[CH2:1][CH3:2])=[N:5][CH:6]=1

Participants

4

Reactant 1

HCID 4418042HCID 4418042, compound

Product 1

HCID 11788486N2,N2-Diethylpyridine-2,5-diamineYield 95%

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 887MethanolSolvent

Procedure

40 g of the 2-diethylamino-5-nitropyridine was subjected to catalytic reduction in one liter of methanol through the use of 2 g of 10% Pd-C. The catalyst was removed by filtration, and the filtrate was concentrated to give 32 g of 5-amino-2-diethylaminopyridine (yield: 95% oleaginous form).

Workup

  1. customThe catalyst was removed by filtration
  2. concentrationthe filtrate was concentrated

Sources & evidence

ORD record
ord-98b4d69397f9412cba7d6391f3f49d1b
Source dataset
uspto-grants-1998_02
Patent number
US05714614

Reaction notes

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