Water → HCID 19704410, compound

HRID 861667Notes

Reaction equation

HRID 861667 reaction equation
C[O:2][C:3]([CH2:5][CH2:6][N:7]([CH:31]1[CH2:36][C:35]([CH3:38])([CH3:37])[NH:34][C:33]([CH3:40])([CH3:39])[CH2:32]1)[CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][N:14]([CH2:25][CH2:26][C:27]([O:29]C)=[O:28])[CH:15]1[CH2:20][C:19]([CH3:22])([CH3:21])[NH:18][C:17]([CH3:24])([CH3:23])[CH2:16]1)=[O:4].O>CCCCCC>[C:3]([CH2:5][CH2:6][N:7]([CH:31]1[CH2:36][C:35]([CH3:38])([CH3:37])[NH:34][C:33]([CH3:40])([CH3:39])[CH2:32]1)[CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][N:14]([CH2:25][CH2:26][C:27]([OH:29])=[O:28])[CH:15]1[CH2:20][C:19]([CH3:22])([CH3:21])[NH:18][C:17]([CH3:23])([CH3:24])[CH2:16]1)([OH:4])=[O:2]

Participants

4

Reactant 2

HCID 962WaterHCID 19704417HCID 19704417, compound3×

Product 1

HCID 19704410HCID 19704410, compoundYield 93.5%

Reagents, catalysts & solvents 1

HCID 8058HexaneSolvent

Procedure

To a four-necked flask equipped with a stirrer and a reflux condenser were added 26.3 g (46 mmoles) of N,N'-bis(2-methoxycarbonylethyl)-N,N'-bis(2,2,6,6-tetramethyl-4-piperidyl)-1,6-hexanediamine (Compound A) obtained in Example 1 and 100 g of water. The resulting mixture was stirred at room temperature. After dissolution of Compound A was confirmed, 100 ml of hexane was added to separate the reaction mixture into two layers. The aqueous layer of the two layers was isolated and concentrated to obtain 23 g (43 mmoles) of Compound C in a yield of 92%.

Workup

  1. customTo a four-necked flask equipped with a stirrer and a reflux condenser
  2. customto separate the reaction mixture into two layers
  3. customThe aqueous layer of the two layers was isolated
  4. concentrationconcentrated

Sources & evidence

ORD record
ord-cf40294d6b1b4dfda0603cd8bcb306b4
Source dataset
uspto-grants-1998_02
Patent number
US05714612

Reaction notes

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