反应详情

A mixture of 2.5 g of Amberlyst A-15, 71.0 g (0.763 mol) of thioglycolic acid and 109.8 g (0.843 mol) of 2-ethylhexanol is heated as described in Example 1, using a water separator, until no further water passes over. The residue is neutralized with 15 ml of a 10% sodium bicarbonate solution at 25° C. and washed with 15 ml of a 3% sodium chloride solution. After the aqueous phase (31.9 g of wash water polluted with thioglycolic acid) has been removed, the residue is distilled under reduced pressure (8.5 mbar) at an overhead temperature of 105° C. 129.5 g (82%) of the product are obtained with first runnings of 16.1 g and a residue of 4.9 g.

1. temperatureis heated
2. washwashed with 15 ml of a 3% sodium chloride solution
3. customAfter the aqueous phase (31.9 g of wash water polluted with thioglycolic acid) has been removed
4. distillationthe residue is distilled under reduced pressure (8.5 mbar) at an overhead temperature of 105° C