Dichloromethane → N-tert-butyl-5-methoxy-1-(4-(trifluoromethyl)phenyl)-3,4-dihydroisoquinoline-2(1H)-carboxamide
Reaction equation
[C:23]([CH3:24])([CH3:25])([CH3:26])[N:27]=[C:28]=[O:29].[CH3:1][O:2][c:3]1[c:4]2[c:9]([cH:10][cH:11][cH:12]1)[CH:8]([c:13]1[cH:14][cH:15][c:16]([C:19]([F:20])([F:21])[F:22])[cH:17][cH:18]1)[NH:7][CH2:6][CH2:5]2.[Cl:30][CH2:31][Cl:32]>>[CH3:1][O:2][c:3]1[c:4]2[c:9]([cH:10][cH:11][cH:12]1)[CH:8]([c:13]1[cH:14][cH:15][c:16]([C:19]([F:20])([F:21])[F:22])[cH:17][cH:18]1)[N:7]([C:28]([NH:27][C:23]([CH3:24])([CH3:25])[CH3:26])=[O:29])[CH2:6][CH2:5]2Participants
4
Sources & evidence
- ORD record
- ord-474b18f539554f758602b9075126a041
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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