Hydrochloric Acid → HCID 10811900, compound

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Reaction Steps

To a solution of ethyl α-{(S)-2-benzyloxycarbonylamino-3-[4-(5H-dibenzo[a,d]cyclohepten-5-ylidene)piperidin-1-yl]propionylamino}acetate(1 g, 1.7 mmol) in 20 ml ethanol was added 20 ml of 1N NaOH solution. The mixture was stirred at room temperature for 3 hours and acidified with conc. HCl. The mixture was stirred at room temperature for another hour. After neutrallization with NaHCO3, the white precipitate was collected by filtration and dried in vacuum. Recrystallization from methanol afforded the title compound as a white crystalline. Yield: 0.5 g (69%).

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