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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 861875Generated: October 25, 2026

Prenderol → 5,5-Diethyl-2-(4-nitrobenzyl)-1,3,2-dioxaphosphorinan-2-oxide

https://huagongshe.com/reaction/861875

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPrenderolHCID 8284—
Reactant(4-Nitro-benzyl)-phosphonic acidHCID 5180708—
Product5,5-Diethyl-2-(4-nitrobenzyl)-1,3,2-dioxaphosphorinan-2-oxideHCID 18928100—

Reaction Steps

4-Nitrobenzylphosphonic acid and 2,2-diethyl-1,3-propanediol were treated in the same manner as in Reference Example 20 to yield 5,5-diethyl-2-(4-nitrobenzyl)-1,3,2-dioxaphosphorinan-2-oxide, which was then recrystallized from ethanol-hexane to yield colorless prisms having a melting point of 159°-160° C.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05716944
Source datasetuspto-grants-1998_02
ORD IDord-fda0ac62c8d74173872038bd0fdd5d72
Source noteuspto-grants-1998_02