HuagongsheHuagongshe Chemistry Print Report · For research reference only
1,4-Butane sultone → HCID 19700575, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1,4-Butane sultone | HCID 15411 | — |
| Reactant | HCID 3999913 | HCID 3999913 | — |
| Solvent | Methyl Isobutyl Ketone | HCID 7909 | — |
| Product | HCID 19700575 | HCID 19700575 | 71.5% |
Reaction Steps
After a mixture of [4-fluorophenyl-(2-pyridyl)methyl]piperazine (2.71 g), 1,4-butanesultone (4.08 g) and isobutylmethylketone (60 ml) is heated at reflux temperature for 20 hours, precipitated crystals are collected by filtration and recrystallized from ethanol-acetone to give the title compound (2.91 g, 71.5%). mp. 231°-232° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05716950 |
| Source dataset | uspto-grants-1998_02 |
| ORD ID | ord-8261f78e0e6f4ebbbbc5e273982b29bf |
| Source note | uspto-grants-1998_02 |